Non sedating antihistamines urticaria treatment


21-Oct-2017 13:58

The EAACI/GA²LEN/EDF/WAO guideline advises that a 4-fold (weight-adjusted) dose increase may be used.The BSACI guidelines note that cetirizine may be more effective than the other antihistamines in chronic urticaria.If higher than standard doses of antihistamines are to be considered, incremental up-dosing is advised.An upper limit for increasing the dose of non-sedating antihistamine is not specified in the BSACI guidelines.If indicated, challenges are coordinated with safety as the highest priority.National Jewish Health has a state-of-the-art challenge facility with extensive experience and an impeccable record in the performance of allergen challenges.However, a small percent of people have hives of unknown origin all the time and are diagnosed with chronic hives (urticaria).

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Therefore, no specific antihistamine is advocated in the guidelines.In most cases, non-sedating antihistamines are prescribed as a first line of treatment and can greatly reduce the hives.



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